The Gut Hormones Your Body Already Makes
GLP-1 is a hormone before it is a medication. What your gut releases after a meal, what ghrelin and PYY actually do, and why the drug version works differently from your own.
Read article →The Dr. Z Journal
Metabolic Health articles
Understanding insulin resistance, blood sugar, and metabolic rate. What standard lab work catches, what it misses, and how to read your own numbers over time.
Metabolic Health
Why Your Cells Stopped Listening to Insulin
Insulin resistance is a signalling failure, not a willpower failure. What happens at the receptor, what GLUT4 does, and why exercise works through a different door entirely.
Read the story →
Explore the journal
Latest insights
Clear answers for complex health questions, written with care.
Your Metabolism Did Not Slow Down in Midlife. Something Else Did.
The best evidence says daily energy expenditure is stable from your twenties to your sixties. What changes in midlife is body composition, not metabolic rate, and that distinction matters.
Read article →
What Actually Happens When You Crash Diet
Severe restriction lowers your metabolic rate by more than the weight loss predicts, and the tissue you lose first is not only fat.
Read article →
Insulin Moves Before the Scale Does
Eat less and move more fails predictably in insulin resistance, and the scale is the last thing to respond. What to measure instead, and why insulin is the starting point.
Read article →
I Want a Faster Metabolism But I Do Not Know Where to Begin
What metabolic rate really is, why crash dieting slows it, and the small number of changes that reliably raise daily energy expenditure.
Read article →
Insulin Resistance: The Ten Years Before Anyone Says the Word Diabetes
Insulin resistance develops silently for years before glucose rises. Learn the early signs, the tests that catch it, and what actually reverses it.
Read article →
Your Labs Came Back Normal. So Why Do You Still Feel Unwell?
Standard blood work is built to detect disease, not early metabolic dysfunction. An endocrinologist explains what normal labs miss and which numbers actually matter.
Read article →