Four Things to Learn While the Medication Is Still Working
Two thirds of the weight lost on semaglutide came back within a year of stopping it. That is not drug failure. It is a missing layer of care, and here is what belongs in it.
Read article →The Dr. Z Journal
Weight & GLP-1 Medicine articles
Evidence-based obesity medicine from a board-certified endocrinologist. How GLP-1 therapies work, what belongs around the prescription, and how to protect muscle while losing fat.
Weight & GLP-1 Medicine
Tirzepatide vs Semaglutide: What Is Actually Different
Semaglutide targets one gut-hormone receptor. Tirzepatide targets two. Which matters more depends entirely on who is asking.
Read the story →
Explore the journal
Latest insights
Clear answers for complex health questions, written with care.
The GLP-1 Pill Is Here. What It Changes, and What It Does Not
Oral semaglutide 25 mg was approved for chronic weight management. An endocrinologist explains the trial results, the dosing rules, and who it suits.
Read article →
The Muscle Question Nobody Raises Before Starting a GLP-1
A meaningful share of weight lost on GLP-1 medications is lean tissue. Here is why it happens, why it matters metabolically, and how to prevent most of it.
Read article →
A GLP-1 Prescription Is Not a Treatment Plan
The WHO now recommends GLP-1 therapy alongside intensive behavioral support. An endocrinologist explains what belongs around the medication and why.
Read article →